Comparative study between ventriculosubgaleal shunt and …
Mar 5, 2024 · Intermittent CSF drainage techniques are utilized for both analysis and treatment of hydrocephalus and may consist of serial lumbar punctures, serial trans fontanelle aspiration, or placement of a transcutaneous tappable reservoir.
Transcutaneous Drug Delivery: A Practical Review
The advantages of transcutaneous drug delivery are avoidance of the gastrointestinal tract and hepatic first-pass biotransformation and metabolism, control of absorption, availability of multiple skin sites to avoid local irritation and toxicity, and improved patient compliance.
A multicenter retrospective comparison of conversion from …
The use of a subcutaneously implanted ventricular access reservoir as a temporizing treatment for PHH has been well described since at least the 1980s. 4, 11 The procedure is technically relatively simple, and allows for controlled transcutaneous CSF withdrawal that can be performed on an as-needed basis, usually guided by clinical parameters.
placement of a transcutaneous tappable reservoir. Conversely, steady CSF drainage could be accomplished by using an External ventricular drain (EVD) or formation of Ventriculosubgaleal shunt (VSGS). VSGS consists of a shunt tube with one end in the lateral ventricles while the other end is inserted into the
Hydrocephalus: historical analysis and considerations for treatment
Intermittent CSF drainage includes serial lumbar punctures, serial transfontanelle aspiration, or placement of a transcutaneous tappable reservoir, while continuous CSF drainage can be achieved by placement of an external ventricular drain (EVD) or …
Cerebrospinal fluid-compensated medication reservoir for an …
May 17, 2013 · In this study, we suggest a new medication reservoir that adopts a cerebrospinal fluid (CSF)-compensating mechanism, such that when a medication is released from the reservoir by a mechanical actuator, native CSF enters into the …
Extending drug release from implants via transcutaneous refilling …
By obviating internal mechanical components, our subcutaneous implant design and transcutaneous refilling method offers a high loading efficiency (LE) of 52%, defined as reservoir size over total implant volume.
A Novel Implantable Cerebrospinal Fluid Reservoir : A Pilot Study
Methods: The newly developed V-Port consists of a non-collapsible reservoir outlined with a titanium cage and a connector for the ventricular catheter to be assembled. It is designed to be better palpated and more durable to multiple punctures than the Ommaya reservoir.
Compressed oxygen is delivered through special tubing to the applicator system. The applicator is a nanodispersion device that has a drug reservoir (customised capsules). The oxygen propels the carrier vehicle and the active ingredients under pressure through the diffuser system, which is held to the skin at. a distance of approximately 2cm.
Transcutaneous Drug Delivery: A Practical Review
Jun 1, 1995 · The advantages of transcutaneous drug delivery are avoidance of the gastrointestinal tract and hepatic first-pass biotransformation and metabolism, control of absorption, availability of multiple skin sites to avoid local irritation and toxicity, and improved patient compliance.