Radiotherapy combined with immunotherapy: the dawn of …
Jul 29, 2022 · Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic effect on remote and non-irradiated tumor deposits, which is called abscopal effect.
Combining Radiation and Immunotherapy: A New Systemic Therapy …
Based on the results of these preclinical studies, several clinical trials have been initiated to assess the efficacy of combining anti-PD1 immunotherapy with radiation therapy. Reports of toxicity associated with immune checkpoint inhibitors in completed trials are summarized below.
Radiation therapy, the immune system and what’s ahead
Sep 27, 2024 · The synergy between radiation therapy and systemic cancer therapies like immunotherapy has long been established, but new research from the Wen Jiang Laboratory leverages a complementary strategy to destroy tumors using a novel antibody-drug conjugate.
Simultaneous radiation and immunotherapy are beneficial for a …
Nov 30, 2022 · New studies investigate how radiation therapy and immunotherapy can be combined to yield positive outcomes in patients with metastatic lung cancer.
Radiation therapy and immunotherapy: what is the optimal …
Novel combinations of radiation with immunotherapy have shown promise in improving outcomes and reducing recurrences by overcoming tumor immune tolerance and evasion mechanisms via boosting the immune system's ability to recognize and eradicate tumor cells.
Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current ...
Numerous preclinical studies have suggested that combining immunotherapy with radiotherapy could be a promising strategy for synergistic enhancement of treatment efficacy. Radiation delivered to the tumor site affects both tumor cells and surrounding stromal cells.
Emerging evidence for adapting radiotherapy to immunotherapy
Jun 6, 2023 · Radiotherapy, the most commonly used oncological treatment, has attracted considerable attention as a combination partner for immunotherapy owing to its well-known and predictable safety profile,...
Radioimmunotherapy (RIT) - RadiologyInfo.org
Radioimmunotherapy (RIT) combines radiation and immunotherapy to treat different types of cancer. RIT pairs radioactive material with a manmade monoclonal antibody specific to the type of cancer cell to create an “agent.”
Radiation With Immunotherapy May Be a Double-Edged Sword
This Viewpoint explains differences between recent studies using radiotherapy with immunotherapy and possible reasons for their different outcomes. [Skip to Navigation] ... Lee P. Radiation With Immunotherapy May Be a Double-Edged Sword—How Can We Learn From Recent Negative Clinical Trials? JAMA Oncol. 2024;10(8):1019–1020. doi:10.1001 ...
Synergizing radiotherapy and immunotherapy: Current …
Here, we examine the available clinical evidence for combination radiation and ICI approaches and propose strategies to expand investigations of the potential synergy in cancer patients. Keywords: Radiotherapy, Radiation therapy, Immune …