Diagnosis of adrenal insufficiency in adults - UpToDate
Aug 20, 2024 · Low CBG — Serum cortisol in patients with suspected low corticosteroid-binding globulin (CBG) due to nephrotic syndrome, sepsis, or cirrhosis should be interpreted with caution.
Determining the etiology of adrenal insufficiency in adults
Determining the etiology of adrenal insufficiency in adults
Hyponatremia and hyperkalemia in adrenal insufficiency
Sep 8, 2023 · The electrolyte disturbances in primary adrenal insufficiency are due to diminished secretion of cortisol and aldosterone (see "Causes of primary adrenal insufficiency (Addison disease)"). A major function of aldosterone is to increase urinary potassium secretion.
Initial testing for adrenal insufficiency: Basal cortisol ... - UpToDate
Sep 8, 2022 · Measurements of serum cortisol soon after wakening (eg, 6 to 8 AM in people who sleep at night) can suggest the diagnosis of adrenal insufficiency. However, these measurements often cannot establish the presence or absence of adrenal insufficiency with certainty and cannot distinguish among the three disturbances in the hypothalamic-pituitary ...
Laboratory assessment of hypothalamic-pituitary-adrenal axis
Apr 2, 2024 · The hypothalamic-pituitary-adrenal (HPA) axis regulates cortisol production. Hypothalamic secretion of corticotropin-releasing hormone (CRH) and vasopressin into the hypothalamic-pituitary portal veins stimulates the release of …
Diagnostic evaluation of adults with hyponatremia - UpToDate
Jul 1, 2024 · INTRODUCTION. Hyponatremia, defined as a serum sodium concentration below 135 mEq/L, is usually caused by a failure to excrete water normally [].In healthy individuals, the ingestion of water does not lead to hyponatremia because suppressed release of antidiuretic hormone (ADH), also called vasopressin, allows excess water to be excreted in a dilute urine ().
Cortisol - UpToDate
…altered hepatic metabolism of cortisol, including hormones, age, disease, obesity, and drugs. Thyroid hormone alters cortisol metabolism. In patients with hyperthyroidism, cortisol clearance is accelerated … ›
Dexamethasone suppression tests - UpToDate
Apr 23, 2024 · Dexamethasone suppression tests (DSTs) are primarily used to screen for excess cortisol production (Cushing syndrome) and are useful in detecting dysregulated cortisol hypersecretion in adrenal incidentalomas.
Patient education: Cushing syndrome treatment (Beyond the Basics)
Mar 13, 2024 · Cushing syndrome occurs when there is an excess of cortisol, a hormone produced by the adrenal glands . This can happen because the pituitary gland releases too much of the hormone corticotropin (ACTH), which stimulates the adrenal glands to make cortisol.
Establishing the diagnosis of Cushing syndrome - UpToDate
Jun 28, 2023 · - Episodic cortisol in Cushing's; RELATED TOPICS. Patient education: Collection of a 24-hour urine specimen (Beyond the Basics) Patient education: Cushing syndrome (Beyond the Basics) Patient education: Cushing syndrome treatment (Beyond the Basics) Anorexia nervosa: Endocrine complications and their management
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