What Is Urothelial Carcinoma? - Cleveland Clinic
Bladder cancer can be high-grade or low-grade: High-grade urothelial carcinoma may be life-threatening. It often comes back after treatment. It may spread into the muscle layer of your bladder, to other areas in your body and to your lymph nodes.
Bladder cancer - Diagnosis and treatment - Mayo Clinic
Mar 29, 2024 · If you have a high-grade, non-muscle-invasive bladder cancer, we generally treat that with a transurethral resection of the bladder tumor, followed by intravesicle therapy, either with chemotherapy or immunotherapy, like BCG.
Bladder Cancer Staging | Bladder Cancer Stages - American Cancer Society
The stage of a bladder cancer is one of the most important factors in deciding how best to treat it and in determining how successful treatment might be. To find the cancer’s stage, doctors try to answer these questions: How far has the cancer grown into the wall of the bladder? Has the cancer reached nearby tissues or organs?
Urothelial carcinoma: 8 insights about this common bladder cancer
May 24, 2024 · High-grade urothelial carcinoma. Urothelial carcinoma is the most common type of bladder cancer. Here, genitourinary medical oncologist Omar Alhalabi, M.D., shares more about this disease, including symptoms, outlook and treatment advances.
Bladder cancer - Symptoms and causes - Mayo Clinic
Mar 29, 2024 · Bladder cancer is almost always one certain type of cancer called urothelial carcinoma, because it starts when urothelial cells that line the inside of the bladder over multiply and become abnormal. Most bladder cancer is caught in …
Treatment of Bladder Cancer, Based on the Stage and Other Factors
These NMIBCs typically have one concerning feature, such as the tumor being larger or high grade, or growing into the connective tissue layer (T1); there being more than one tumor; or a tumor that has recurred (come back). Most often, intravesical therapy (either BCG or chemotherapy) is recommended after the TURBT.
Staging & Grade - Bladder Cancer | Johns Hopkins Pathology
If the cancerous tissue looks very different from healthy tissue, it is called "poorly differentiated" or a "high-grade tumor." Many urologic surgeons classify a tumor’s grade based on the chance that the cancer will recur or grow and spread, called progression. They often plan treatment based on the grade, using the following categories:
Bladder Cancer - StatPearls - NCBI Bookshelf - National Center …
Aug 15, 2024 · Urothelial carcinoma is the most frequent type of bladder cancer, constituting over 90% of cases in industrialized nations. This type of cancer is notably common among older adults, with risk factors including smoking, chemical exposure, and chronic bladder inflammation.
Treatment of Bladder Cancer by Stage - NCI
High-risk bladder cancer might include multiple or large high-grade stage 0a tumors, the presence of carcinoma in situ (stage 0is), and fast-growing stage I tumors. Treatment typically includes TUR with fulguration, followed by intravesical BCG therapy. Sometimes, intravesical BCG is continued for up to 3 years to lower the risk of recurrence.
Pathology Outlines - Invasive urothelial carcinoma
May 13, 2021 · Urothelial carcinoma that has penetrated the basement membrane and invaded into the lamina propria or deeper. Essential features. Histologic characterization and depth of invasion are the most important factors for determining prognosis (Adv Anat Pathol 2015;22:102)