Cortisol dysregulation in obesity-related metabolic disorders
This review highlights recent investigations focusing on the role of dysregulated cortisol physiology in obesity as a potential modifiable mechanism in the pathogenesis of obesity related cardiometabolic disorders. Keywords: obesity, cortisol, mineralocorticoid receptor, metabolic syndrome, hypertension. Introduction
Stress, cortisol, and obesity: a role for cortisol responsiveness in ...
It has now emerged that cortisol responsiveness is an important determinant in the metabolic sequelae to stress. Sheep that are characterized as high-cortisol responders (HRs) have greater propensity to weight gain and obesity than low-cortisol responders (LRs).
Stress and Obesity: Are There More Susceptible Individuals?
Increased long-term cortisol levels, as measured in scalp hair, are strongly related to abdominal obesity and to specific mental disorders. However, not all obese patients have elevated cortisol levels.
Obesity and cortisol: New perspectives on an old theme
Feb 23, 2017 · Importantly, insight into the mechanisms underlying increased cortisol exposure in obesity may lead to a more effective implementation of cortisol-lowering therapies and potential new treatment targets.
Stress, cortisol, and other appetite-related hormones: Prospective ...
To examine whether baseline chronic stress, morning cortisol, and other appetite-related hormones (leptin, ghrelin, and insulin) predict future weight gain and food cravings in a naturalistic longitudinal 6-month follow-up study.
High/low cortisol reactivity and food intake in people with obesity …
Jan 27, 2020 · Thirty-six men and women with obesity (BMI: 33.00 ± 3.23 kg/m²), as well as 36 age- and gender-matched healthy weight controls (BMI: 21.98 ± 1.81 kg/m²) were categorized into high cortisol...
Cortisol, obesity, and the metabolic syndrome: a cross ... - PubMed
Objective: Circulating cortisol and psychosocial stress may contribute to the pathogenesis of obesity and metabolic syndrome (MS). To evaluate these relationships, a cross-sectional study of 369 overweight and obese subjects and 60 healthy volunteers was performed and reviewed the previous literature.
Obesity and cortisol - PubMed
Cortisol in obesity is a much-studied problem. Previous information indicates that cortisol secretion is elevated but that circulatory concentrations are normal or low, suggesting that peripheral disappearance rate is elevated.
Cortisol Belly and How to Get Rid of It - Verywell Health
Oct 23, 2024 · Cortisol belly refers to the accumulation of belly fat caused by chronic exposure to high levels of cortisol. Cortisol plays a key role in helping your body respond to stress, reduce inflammation, and regulate blood pressure, blood sugar, and metabolism.
Glucocorticoids and HPA axis regulation in the stress–obesity ...
Dec 2, 2024 · Chronic stress, characterized by increased long-term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms.