The gastric precancerous cascade - CORREA - Wiley Online Library
Oct 28, 2011 · Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first recognized histologic change is active chronic inflammation, which may persist as such: non-atrophic chronic g...
Gastric intestinal metaplasia and gastric cancer prevention: …
Jan 1, 2024 · The Correa cascade describes the evolution of precancerous mucosal changes that lead to development of GIM, with differentiation of 2 histologic types of GIM (complete and incomplete) and the consequences of each type. The risk of progression to malignancy is higher with incomplete GIM.
Evolution of the Correa's cascade steps: A long-term endoscopic ...
May 1, 2023 · Gastric cancer is the sixth most common cancer and the fourth most common cause of cancer death in the world. 1 Gastric adenocarcinoma develops after a prolonged precancerous process after Helicobacter pylori infection. 2 Correa et al. described this process as a cascade, from chronic gastritis to invasive carcinoma. 3 In order to represent ...
so-called “Correa cascade”) has come into question recently, we review the scientific evidence that strongly supports this long-standing model and propose a new progression model that builds on the Correa cascade. Eradication of H pylori is the most important method for preventing gastric cancer globally, but the effect of eradi-
Incidence of gastric cancer among patients with gastric …
Jul 27, 2015 · The annual incidence increased monotonically with each step in Correa’s cascade, up to 262.8×10 −5 (190.9 to 352.8) in the dysplasia group. With such an incidence, approximately 1 in 19 people will get gastric cancer within 20 years.
Pathways of Gastric Carcinogenesis, Helicobacter pylori Virulence …
Sep 3, 2020 · The Correa model of intestinal type gastric carcinogenesis is a multistep cascade of chronic active gastritis progressing to multifocal AG, IM, low grade dysplasia, high grade dysplasia and finally gastric adenocarcinoma . The Modified Sydney System is an internationally recognized endoscopic and histological system of chronic gastritis ...
The immune microenvironment in gastric adenocarcinoma
Mar 14, 2022 · The Correa cascade was ultimately incorporated into the Sydney Classification system, which describes sequential events in histological terms: chronic inflammation proceeds to intestinal-type...
The gastric precancerous cascade. Pelayo CORREA & M Blanca PIAZUELO. Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA. Invasive gastric carcinoma is preceded by a cascade of precancerous lesions.
Dynamic variations of the gastric microbiota: Key therapeutic …
Mar 15, 2023 · Correa's cascade is a dynamic process in the development of intestinal-type gastric cancer (GC), and its pathological features, gastric microbiota and interactions between microorganisms and their hosts vary at different developmental stages.
Mapping the genomic diaspora of gastric cancer - Nature
Oct 26, 2021 · The Correa cascade posits that normal gastric cells are transformed to malignancy via a stepwise process starting from Helicobacter pylori infection of normal gastric mucosa to chronic-atrophic...