The role of adipose tissue in cardiovascular health and disease
The adipose tissue is now recognized as a crucial regulator of cardiovascular health, mediated by the secretion of several bioactive products, including adipocytokines, microvesicles and gaseous messengers, with a wide range of endocrine and paracrine effects on the cardiovascular system.
Emerging Roles for Adipose Tissue in Cardiovascular Disease
Jul 25, 2018 · Adipose tissue, comprising mainly adipocytes and immune cells, exerts endocrine effects on distant tissues through the secretion of adipokines, such as adiponectin and leptin. This figure highlights 3 novel functions for adipokines that were recently described in ATVB.
The role of adipose tissue in cardiovascular health and disease - Nature
Oct 4, 2018 · In this Review, we summarize the current knowledge of the biology and regional variability of adipose tissue in humans, deciphering the complex molecular mechanisms controlling the crosstalk...
Adipose Tissue, Inflammation, and Cardiovascular Disease
May 13, 2005 · Mounting evidence highlights the role of adipose tissue in the development of a systemic inflammatory state that contributes to obesity-associated vasculopathy and cardiovascular risk.
Adipose Tissue Distribution, Inflammation and Its Metabolic ...
In obesity, adipose tissue becomes dysfunctional, promoting a pro-inflammatory, hyperlipidemic and insulin resistant environment that contributes to type 2 diabetes mellitus (T2DM). Concurrently, similar features that result from adipose tissue dysfunction also promote cardiovascular disease (CVD) by mechanisms that can be augmented by T2DM.
Role of Epicardial Adipose Tissue in Cardiovascular Diseases: A …
Cardiovascular diseases (CVDs) are the leading causes of death worldwide. Epicardial adipose tissue (EAT) is one of the most important risk factors for cardiovascular events and a promising new therapeutic target in CVDs. Here, we summarize the ...
Adipose Tissue Distribution, Inflammation and Its Metabolic ...
Feb 25, 2020 · In obesity, adipose tissue becomes dysfunctional, promoting a pro-inflammatory, hyperlipidemic and insulin resistant environment that contributes to type 2 diabetes mellitus (T2DM). Concurrently, similar features that result from adipose tissue dysfunction also promote cardiovascular disease (CVD) by mechanisms that can be augmented by T2DM.
Epicardial adipose tissue, metabolic disorders, and cardiovascular ...
Epicardial adipose tissue (EAT) is located between the myocardium and visceral pericardium. The unique anatomy and physiology of the EAT determines its great potential in locally influencing adjacent tissues such as the myocardium and coronary arteries.
Epicardial adipose tissue in contemporary cardiology - Nature
Mar 16, 2022 · Epicardial adipose tissue (EAT) has anatomical and functional interactions with the heart owing to the shared circulation and the absence of muscle fascia separating the two organs. EAT...
The Role of Adipose Tissue in Cardiovascular Disease:
In summary, the current translational study elegantly bridges basic and clinical science to demonstrate the role of adipose tissue as a potential endocrine mediator of cardiovascular health. Taken together with prior literature, there is now growing evidence to implicate ceramides in pathways contributing to cardiovascular disease.
- Some results have been removed