Animal modeling for myopia - PubMed
Jun 5, 2024 · Various experimental animal models have been developed to mimic human myopia, including chickens, rhesus monkeys, marmosets, mice, tree shrews, guinea pigs and zebrafish. Studies using these animal models have provided evidences and perspectives on the regulation of eye growth and refractive development.
Animal models in myopia research - PubMed
Contrary to previous assumptions about the mechanisms of myopia, these animal models suggested that eye growth is visually controlled locally by the retina, that an afferent connection to the brain is not essential and that emmetropisation uses more sophisticated cues than just the magnitude of retinal blur.
Animal modeling for myopia - ScienceDirect
Nov 1, 2024 · Studies in experimental myopic animals have provided valuable insights into the mechanisms, risk factors, and treatment for myopia. However, each animal model has its own advantages and disadvantages due to species differences.
Animal Models of Experimental Myopia: Limitations and
Jul 29, 2021 · This perspective means that the ideal animal model should reproduce the developmental features of human myopia in the time course of change in the ocular determinants of refraction and also use methods of inducing experimental myopia …
A highly efficient murine model of experimental myopia
Feb 1, 2018 · Here we report a highly practical and reproducible lens-induced myopia model by specially designed frames and lenses for mice. A lens power dependent myopic induction in mice was shown...
Animal Models of Myopia: Learning How Vision Controls the Size …
Apr 1, 1999 · Animal models appear to emulate physiological myopia. The second broad category of myopia is “pathological,” “progressive,” or “degenerative” myopia, which involves an “abnormal lengthening of the eye” ( Curtin 1985 ).
Animal Models of Myopia: Learning How Vision Controls the …
Although several species have been examined, three have emerged as primary models and have played complementary roles: tree shrews (mammals closely related to primates), chicks, and monkeys. Each has advantages and disadvantages.
Animal Models of Experimental Myopia: Limitations and
Nov 11, 2013 · Despite the many limitations and cautions on the use of animal models of experimental myopia, studies on animal models can investigate issues that cannot be addressed in humans – in particular animal models of experimental myopia can be used to elucidate details of the molecular and cellular processes involved, which may open up opportunities ...
Animal models in myopia research - Wiley Online Library
Nov 27, 2015 · Contrary to previous assumptions about the mechanisms of myopia, these animal models suggested that eye growth is visually controlled locally by the retina, that an afferent connection to the brain is not essential and that emmetropisation uses more sophisticated cues than just the magnitude of retinal blur.
Animal models as windows into the pathogenesis of myopia: …
Nov 12, 2024 · Since the 1970s, numerous research teams have attempted to establish animal models of myopia to further explore its molecular mechanisms and methods for preventing and controlling myopia. Common animal models of myopia …