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  1. Ketamine
    KetamineDis dissociative anesthetic
    Side effectsDosageIndicationsCompositionUsesMechanism of actionClinical trialsCost
     
  2. Wikipedia
    https://en.wikipedia.org › wiki › Ketamine

    Ketamine - Wikipedia

    • Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and in pain management. Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects. At anesthetic doses, ketamine induces a state of dissociative anesthesia, a trance-like state provid… See more

    Medical uses

    The use of ketamine in anesthesia reflects its characteristics. It is a drug of choice for short-term procedures when muscle relaxation is not required. The effect of ketamine on the respiratory and circulatory systems is … See more

    Contraindications

    Some major contraindications for ketamine are:
    • Severe cardiovascular disease such as unstable angina or poorly controlled hypertension
    • Increased intracranial or intraocular pressure … See more

    Ketamine Treatment for Depression - Child Mind Institute
    Ketamine works by binding to brain receptors, increasing connectivity among neurons, and influencing mood. Its advantage is its rapid symptom relief, often within an hour, compared to wee…
    Child Mind Institute · https://childmind.org/articl…
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  2. Britannica
    https://www.britannica.com › science › ketamine

    Ketamine | Definition, Uses, & Facts | Britannica

  3. Association of American Universities (AAU)
    https://www.aau.edu › research-scholarship › featured...

    How can low-dose ketamine, a ‘lifesaving’ drug for major …

  4. ScienceDirect
    https://www.sciencedirect.com › org › science › article › abs › pii

    Insights for the Next Generation of Ketamine for the Treatment of ...

  5. Nature
    https://www.nature.com › articles

    Enhancing proteasome activity by NMDAR antagonists …

    3 days ago · Modulation of intrinsically disordered proteins (IDPs) Levels and Proteasome Activity by NMDA Receptor Antagonists.(A) Ketamine (500 µM) and (B) memantine (10 µM) reduce the levels of the cell ...

  7. Child Mind Institute
    https://childmind.org › article › ketamine-tre…

    Ketamine Treatment for Depression - Child …

    Dec 26, 2024 · Ketamine works by binding to brain receptors, increasing connectivity among neurons, and influencing mood. Its advantage is its rapid symptom relief, often within an hour, …

  8. Medscape Education
    https://www.medscape.org › viewarticle

    The APA Guidelines on Ketamine Use for Depression

    2 days ago · A new review highlights promise and potential problems of treatment with ketamine and esketamine in managing treatment-resistant depression. This activity is intended for primary care clinicians, psychiatrists, pharmacists, …

  9. Springer
    https://link.springer.com › article

    Mitochondrial damage causes inflammation via cGAS-STING

  10. Tidsskrift for Den norske legeforening
    https://tidsskriftet.no › en › perspectives › ...

    Ketamine for depression – evidence and proposals for …

    Jan 8, 2025 · Ketamine consists of a racemic mixture of arketamine and esketamine and is a non-competitive N-methyl-D-aspartate (NMDA) glutamate receptor antagonist which produces a dosage-dependent analgesic and …

  11. The Alcohol and Drug Foundation
    https://adf.org.au › drug-facts › ketamine

    Ketamine - Alcohol and Drug Foundation

    Jan 6, 2025 · Ketamine is a dissociative drug, which means it causes people to feel separated or detached from their body or physical environment. Dissociatives are similar to …

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