Programmed cell death during neuronal development: the
Apr 25, 2014 — In this article, we review the key papers published in the past few years, covering all aspects of apoptosis regulation in sympathetic neurons and focusing, in particular, on how signalling...
Programmed Cell Death in Neurodevelopment - Cell Press
Feb 23, 2015 — Programmed cell death (PCD) is an evolutionarily conserved contributor to nervous system development. In the vertebrate peripheral nervous system, PCD is the basis of the neurotrophic theory, whereby cell death results from a surplus of neurons relative to target and competition for neurotrophic factors.
Molecular mechanisms of cell death in neurological diseases
Jun 7, 2021 — Tightly orchestrated programmed cell death (PCD) signalling events occur during normal neuronal development in a spatially and temporally restricted manner to establish the neural...
Programmed Cell Death in Neuronal Development | Science
Apr 5, 2013 — Programmed cell death, or apoptosis, accompanies the development of many tissues, including the vertebrate nervous system. Most neurons are eliminated soon after synaptic contacts have been made between the neurons and their targets.
Molecular mechanisms of cell death in neurological diseases
Tightly orchestrated programmed cell death (PCD) signalling events occur during normal neuronal development in a spatially and temporally restricted manner to establish the neural architecture and shaping the CNS.
Programmed cell death during neuronal development: the
Developing sympathetic neurons of the superior cervical ganglion are one of the best studied models of neuronal apoptosis. These cells require nerve growth factor (NGF) for survival at the time that they innervate their final target tissues during …
Programmed Cell Death in Neurodevelopment - ScienceDirect
Feb 23, 2015 — Programmed cell death (PCD) is an evolutionarily conserved contributor to nervous system development. In the vertebrate peripheral nervous system, PCD is the basis of the neurotrophic theory, whereby cell death results from a surplus of neurons relative to target and competition for neurotrophic factors.
Programmed Cell Death and the Control of Cell Survival ... - Science
Oct 29, 1993 — During the development of the vertebrate nervous system, up to 50 percent or more of many types of neurons normally die soon after they form synaptic connections with their target cells.
Programmed cell death in the peripheral and central nervous system. In both the PNS and CNS, pro-grammed cell death occurs predominantly when the young neurons contact their designated target tissues (e.g., skin, or target neuron).
Neuronal Cell Death Mechanisms in Major Neurodegenerative …
Apoptosis is a type of programmed cell death (PCD). The cytomorphological features of an apoptotic cell include shrinkage, chromosome condensation and DNA fragmentation [22,23,24].