See related article at Key points Targeted therapy and immunotherapies are now treatment mainstays for an increasing number ...

In research published in this issue of CMAJ, Mah and colleagues summarize clinicians’ experiences of providing care for patients whose presenting illness is not acute and for whom admission to ...

Results: In 2024, the number of new cancer cases and deaths from cancer are expected to reach 247 100 and 88 100, respectively. The age-standardized incidence rate (ASIR) and mortality rate (ASMR) are ...

See related article at In a related analysis, Abdel-Rahman and colleagues[1][2] discuss how the marked improvement in quantity and quality of life experienced by some people with cancer who receive ...

An 81-year-old man presented to the emergency department after 2 episodes of uncontrollable shaking, each lasting several minutes, accompanied by a sensation of extreme cold. He and his partner stated ...

Jane S. Thornton, William N. Morley and Samir K. Sinha Physical activity is a modifiable risk factor for more than 30 chronic conditions relevant to the older adult; 150 minutes per week of moderate ...

Velina Tzankova, Werner J. Becker and Tommy L.H. Chan Migraine is a leading cause of disability across all age groups. Routine imaging is not recommended in patients with migraine who have no red ...

A 32-year-old woman presented to our emergency department 2 days after the onset of bilateral hand swelling. Two weeks earlier, her 8-year-old son had had an erythematous rash on both cheeks. A week ...

Transgender individuals experience high rates of violence, discrimination and homelessness. Psychiatric disorders should be managed before or concurrent with medical transition for gender dysphoria.

Chimeric antigen receptor T-cell therapy (CAR-T) is a targeted, gene-edited cell therapy for cancer that is approved in Canada for relapsed or refractory high-grade B-cell lymphoma and B-cell acute ...

In January 2018, Dr. Tyndall advocated for prescribing hydromorphone as a response to the presence of illicitly manufactured fentanyl in the street opioid supply.1 Two years later, the opioid crisis ...

Delirium occurs in 30%–50% of adults aged 65 years or older admitted to hospital, and may be hypoactive (lethargy, reduced psychomotor functioning), hyperactive (agitation, hallucinations) or mixed.1 ...