Background The diagnosis and management of pneumonia is often challenging due to its overlapping clinical presentations with ...

Correspondence to Dr John Field, Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, Department of Molecular and Clinical Cancer Medicine, Institute of ...

Background CT pulmonary angiography (CTPA) is widely regarded as the gold standard test for suspected pulmonary embolism (PE) and is increasingly used as an all-inclusive diagnostic tool for patients ...

Introduction Although formal patient registries in complex home ventilation have long been recommended 1, recent review found few centres maintain accurate records of activity 2. However, the ability ...

1 Royal Brompton & Harefield Hospitals, Guy’s and St.Thomas’ NHS Foundation Trust, London, UK Since the Guideline, there is deeper understanding of referral characteristics, outcome measures, patient ...

BACKGROUND Varicella is 25 times more likely to be complicated by pneumonia in adults than in children. Data on changes in lung function following pneumonia are limited. This study was undertaken to ...

Introduction and objectives Airway sensory nerves involved in the cough reflex may be mediated by adenosine triphosphate (ATP) agonism of P2X purinoceptor 3 (P2X3) receptors. Transient receptor ...

Introduction The PiSZ genotype results in less severe deficiency of alpha-1 antitrypsin (AAT) than PiZZ. Less is known about phenotypic and prognostic features. Methods We studied 699 PiZZ, 126 PiSZ ...

1 Salford Royal Hospital, The Northern Care Alliance NHS Foundation Trust, Salford, UK 2 The Christie NHS Foundation Trust, Manchester, UK 3 Manchester University NHS Foundation Trust, Manchester, UK ...

Introduction Identifying acute hypercapnic respiratory failure is crucial in the initial management of acute exacerbations of COPD. Guidelines recommend obtaining arterial blood samples but these are ...