A clinical trial is a research study that prospectively assigns health-related interventions to people (or groups) typically using randomisation to evaluate the effects on health outcomes.

Abusive head trauma (AHT) affects one in 4000–5000 infants every year and is one of the most serious forms of physical child abuse that has a high associated mortality and morbidity. Differentiating ...

1H-Magnetic Resonance Spectroscopy (MRS) is a novel advanced imaging technique used as an adjunct to MRI to reveal complementary non-invasive information about the biochemical composition of imaged ...

Clinical guidelines can lead to improved health care, but many guidelines are not effectively implemented. We examine what is involved in implementing guidelines and the evidence about the commonest ...

Assessment of ticsADHD, attention-deficit hyperactivity disorder; CGH comparative genomic hybridisation; OCD, obsessive-compulsive disorder; TS, Tourette syndrome.

The National Institute for Health and Clinical Excellence neonatal jaundice guidelines recommend checking the bilirubin level in all infants with visible jaundice. The gold standard for this ...

Tuberous sclerosis complex is a complex childhood disorder characterised by the formation of hamartomas in multiple organs. Annual review of this disease is recommended to monitor the development of ...

Back pain in childhood is relatively unusual, although as a child matures through adolescence it becomes much more common. At any age, potentially serious illnesses need to be excluded. There are some ...

Pulmonary causes of central cyanosisTable 5 Pulmonary causes of central cyanosis ...

Table 7 Indications, efficacy and monitoring requirements of medications used for treatment of chronic tic disorders and TS ...

Chest radiographs showing left-sided parapneumonic effusion due to pneumococcal pneumonia, (A) before and (B) after drainage.

Classification of tics by descriptionTable 1 Classification of tics by description ...