HF decompensation is characterized by increased left atrial pressure (LAP) causing symptomatic pulmonary congestion and frank edema. 2 The possible precipitants for acute HF are numerous, but they ...

Background—Although frequently assessed in trials and clinical practice, hemodynamic response to therapy has never been validated as a surrogate end point for clinical events in pulmonary arterial hy ...

The origin and pathophysiology of CVT in the pediatric population is still poorly understood, mainly because of its low incidence, which is estimated at 0.67 per 100 000 children. 1 The disease is ...

Background: Extracellular hemoglobin and cell-free heme are toxic breakdown products of hemolyzed erythrocytes. Mammals synthesize the scavenger proteins haptoglobin and hemopexin, which bind ...

Dokuchaev A, Panfilov A and Solovyova O (2020) Myocardial Fibrosis in a 3D Model: Effect of Texture on Wave Propagation, Mathematics, 10.3390/math8081352, 8:8, (1352) Huang C, Knighton N, Timmins L ...

Methods and Results— Using a modification of a previously validated risk prediction model based on routine clinical variables, we examined the relationship between baseline predicted mortality risk ...

Atherosclerosis remains a major health problem in the United States, with significant morbidity and an estimated annual mortality of 500 000 deaths from coronary artery disease alone. 1 The lesions in ...

Abstract Background— Platelet-activating factor acetylhydrolase (PAF-AH), also denoted as lipoprotein-associated phospholipase A2, is a lipoprotein-bound enzyme that is possibly involved in ...

Abstract Background —In the presence of ST-elevation myocardial infarction, patients with successful epicardial reperfusion (TIMI 3 flow) but persistent ST elevation on a 12-lead ECG are at high risk ...

Abstract Current data and guidelines recommend treating abnormal blood lipids (ABL) to goal. This is a complex process and requires involvement from various healthcare professionals with a wide range ...

From the Winters Center for Heart Failure Research (D.L.M.), Baylor College of Medicine and the Houston VA, Houston, Tex; Department of Cardiology, Western Infirmary ...

Background— Previous studies suggest that management of ambulatory hemodynamics may improve outcomes in chronic heart failure. We conducted a prospective, observational, first-in-human study of a phy ...