Reporting emerged earlier on Thursday noting that 49ers running back Isaac Guerendo is unlikely to play in Sunday's game ...

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because ...

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

The San Francisco 49ers are poised to unveil their fourth starting running back of the season Sunday. The latest next man up ...

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.

ESPN insider Adam Schefter reported that San Francisco 49ers rookie running back Isaac Guerendo is unlikely to play against ...

After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the ...

Add running back Isaac Guerendo to the San Francisco 49ers' unfathomable list of injuries heading into Sunday's game at the ...

Should I start or sit Patrick Taylor Jr. for fantasy football in Week 16? Read our fantasy football start 'em, sit 'em picks ...

The FFHH crew evaluate the running back rooms in San Francisco and New Orleans with both teams dealing with key injuries in ...

"Patrick Taylor Jr.is a fantasy football waiver wire pickup option at running back. Target him as a free agent add off ...

Isaac Guerendo rushed for 57 yards on 16 carries (3.6 yards per carry), adding four receptions for 18 yards. George Kittle led the receiving charge, catching four passes for 61 yards. Learn more ...