Claudin-1, a tight junction protein expressed in human liver, has been identified as an essential entry co-factor for hepatitis C virus. Like the CD81 co-receptor, claudin-1 spans the cell ...

Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP. Nature Communications , 2024; 15 (1) DOI: 10.1038/s41467-024-46706-w Cite This Page : ...

Porcine reproductive and respiratory syndrome virus (PRRSV) continues to devastate the global swine industry, yet the ...

Hence, ACE2 acts as a cellular doorway—a receptor—for the virus that causes COVID-19. ... The virus reaches the lungs after entry in the nose or mouth. ANG II drives lung injury.

However, at present this coronavirus, called NeoCoV and a similar virus, PDF-2180, only weakly bind to human ACE2 cell receptors as an entry point into cells.

DENV Attachment: Multiple Cell Receptors? The events involved in virus entry comprise virion binding to the cell surface followed by penetration into the cytoplasm. The success of both sequential ...

To cross-check this, the researchers used cell cultures in which the co-receptor was over-produced. In this case, more infections occurred than in untreated cells. A protein plays a major role as a co ...

In bats, two close virus relatives of the coronavirus MERS-CoV, the cause of Middle-East Respiratory Syndrome, use the ACE2 receptor as an entry point into bat cells. These receptors have some ...

More information: Kaho Shionoya et al, Structural basis for hepatitis B virus restriction by a viral receptor homologue, ...

This suggests that the binding of the virus to the ACE2 receptor is the decisive step in infection." ... Coronaviruses Use ACE2 Monomers as Entry-Receptors. Angewandte Chemie International Edition.

New research shows that the closest bat virus relatives of the human Middle-East Respiratory Syndrome (MERS) coronavirus efficiently bind to bat ACE2 receptors as an entry point into these cells.

Future Virology. 2008;3(5):471-479. Lipid raft-mediated endocytosis independent of dynamin; The nonclathrin, noncaveolar-mediated pathway independent of lipid rafts, in which dynamin participation ...