Enhertu (fam-trastuzumab deruxtecan-nxki) is a brand-name intravenous (IV) infusion that’s prescribed for certain types of cancer in adults. As with other drugs, Enhertu can cause side effects ...

glycosylation and IgG binding affinity and signaling - resulting in antibody-dependent cellular cytotoxicity - ADCC. The work builds off prior findings from this group about the general impact of ...

*p < 0.001; **p < 0.0001; ***p = 0.01; ****p < 0.01 vs comparator regimen.CClR: Cyclophosphamide + cladribine + rituximab; ClR: Cladribine + rituximab; CR: Complete ...

Trastuzumab is a monoclonal antibody targeted against the human epidermal growth factor receptor (HER) 2 tyrosine kinase receptor, which is overexpressed in approximately 25% of invasive breast ...

Pertuzumab and trastuzumab are used to treat breast cancer. Often a combined treatment called Phesgo® is used instead. Phesgo® contains pertuzumab, trastuzumab, and hyaluronidase-zzxf. It is best to ...