Researchers at the University of Gothenburg, Sweden, in collaboration with colleagues in China, have discovered an ...

Enabling protein degradation with small-molecule drugs has emerged as an innovative approach to the development of therapeutics against otherwise intractable targets. Two landmark studies that ...

It does so with the help of a zinc finger, a small protein wrapped around a zinc molecule. Orkin's team has now reported the crystal structure of the BCL11A tetramer and suggested several ways to ...