New tool to map protease specificity may pave the way for improved treatments
FMI researchers have developed a new tool that maps how proteases—enzymes that process proteins—cut their targets. This ...
eLife4h
Single cell transcriptomics reveals early photoreceptor states, cell-specific transcript isoforms, and cancer-predisposing features
Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...
The EMBO Journal2d
Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB
MMPP was shown to cross the glomerular filtration barrier and to accumulate in renal tubules, leading to reduced oxidative ...
eLife4d
Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...
BioSpace3d
In-Vitro Diagnostics Enzymes Market Size to Surpass USD 4.10 Bn by 2033
Thermo Fisher Scientific, Sigma-Aldrich, QIAGEN, EKF Diagnostics, etc. are some dedicated diagnostics manufacturing companies that provide several enzymes and enzyme master mix solutions to conduct ...