FMI researchers have developed a new tool that maps how proteases—enzymes that process proteins—cut their targets. This ...

This month, we feature two people who have been in the field since its inception: one developing assays at a pharmaceutical ... molecules are recognized by enzymes, and how enzymes generate ...

The longest-used assay depends on ingredients from ... This binding changes factor C’s shape and activates its protease abilities. Now active, the enzyme cleaves itself and then other proteins ...

[13] HIV genotypic assays detect specific mutations or nucleotide substitutions in the gag-pol region of the HIV-1 genome. This region encodes for the reverse transcriptase and protease enzymes ...