Programmed Cell Death and Cancer . Cancer cells can evade programmed cell death, allowing them to persist and proliferate in the body. For example, many hematological and solid tumor cancers have ...

Researchers from Helmholtz Munich and the Technical University of Munich have developed a novel method to track cancer treatment responses in individual cells—without the need for dyes or labels.

Gynecological clear cell cancers (CCCs), very aggressive forms of ovarian and endometrial malignancies, respond poorly to chemotherapy.  The low respo | Cancer ...

The soluble Bax protein is responsible for the clearance of old or diseased cells, and when activated, it perforates the cell mitochondrial membrane to form pores that trigger programmed cell death.

The findings were published Oct. 14 in the Nature journal Cell Death & Differentiation. CD95 receptors, also known as Fas, are called death receptors. These protein receptors reside on cell membranes.

Cell death discovery could lead to next-gen drugs for neurodegenerative conditions May 12, 2025 Survival protein may prevent collateral damage during cancer therapy ...

Flashback Foreword: Single-Agent Anti–Programmed Cell Death Protein 1 Therapy for Refractory Solid Tumors. JCO 41 , 713-714 (2023). DOI: 10.1200/JCO.22.02437 ...

The US Food and Drug Administration (FDA) has placed a partial clinical hold on the phase 3 PRESERVE-003 trial of BNT316/ONC-392 (gotistobart, BioNTech and OncoC4) for non–small cell lung cancer ...

There are several programmed cell death pathways that lead to cellular self-destruction, either for developmental processes, tissue maintenance, or stress responses. These include apoptosis, ...