Neonatal Neurosciences Unit, Division of Paediatrics and Gynaecology, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Rd, London W12 ONN If you wish to reuse any or all of this ...
A team of researchers at Broad Institute of MIT and Harvard, in a long-term project that has included industry collaborators ...
In AD, tau protein becomes hyperphosphorylated, impairing its microtubule-binding activity, resulting in microtubule destabilization, neurofibrillary tangle development, and neuronal death.
Going a step further, we also showed that when these proteins are absent, normal neuronal development is hampered ... to play a crucial role in cellular processes such as cell proliferation, cell ...
In the first category, aging is essentially an accident; an accumulation of damage and wear and tear to the body which eventually leads to death. In contrast, programmed aging ... and mechanisms of ...
Programmed cell death-1, or PD-1, has become a headline-grabbing molecule best known for its role in cancer immunotherapies ...
An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this ...
"If this complex is disrupted, it can lead to the death of the affected cell. For this reason ... Defective splicing variants might also play a role in the development of neurodegenerative diseases ...