snmjournals.org18d
PET Imaging of PD-L1 Occupancy for Preclinical Assessment of the Efficacy of Combined Anti–PD-L1 Immunotherapy and Targeted Therapy
Journal of Nuclear Medicine February 2025, jnumed.124.268586; DOI: https://doi.org/10.2967/jnumed.124.268586 ...
ascopubs.org20d
Checkpoint blockade as neoadjuvant strategy: A single-arm meta-analysis of dual PD-1/PD-L1 and CTLA-4 inhibition in urothelial cancer.
Safety and efficacy of FGFR inhibitors in urothelial carcinoma: A systematic review and meta-analysis. Efficacy and safety of tislelizumab (T) combined with gemcitabine and cisplatin (GC) for patients ...
Frontiers21d
AWT020: a novel fusion protein harnessing PD-1 blockade and selective IL-2 Cis-activation for enhanced anti-tumor immunity and diminished toxicity
The improved tolerability of AWT020 facilitates the complete blockade of the PD1-PD-L1 interaction, thereby preventing the inhibitory signal mediated by PD-1. Concurrently, IL-2R is activated to ...
Wall Street Journal23d
China’s Rehearsals for a Blockade of Taiwan
The goal is to cut off Western support for Taiwan in a blockade or invasion. A military exercise in October 2024 was practice for a blockade. And in May 2024 China encircled Taiwan and practiced a ...
WTEN26d
Albany PD: 2 teens injured in Myrtle Avenue shooting
ALBANY, N.Y. (NEWS10) — Albany police are investigating a Tuesday evening shooting. It took place around 6:25 p.m. on Myrtle Avenue near Grand Street. Police said two boys under the age of 15 ...
ahajournals.org27d
Novel Therapeutic Approach Targeting CXCR3 to Treat Immunotherapy Myocarditis
ICIs block the interaction between immune checkpoints such as PD1 (programmed cell death-1) and CTLA4 (cytotoxic T-lymphocyte ... Using selective blockade of CXCL9 and CXCL10, we determined that only ...
CBC.ca28d
Sentencing date for final accused in 2022 Coutts blockade to be set in 2 weeks
The last outstanding case tied to the 2022 Coutts, Alta., border blockade is likely to be wrapped up in early March with the sentencing of one of the men convicted. Alex Van Herk, who was found ...