p53 is a common denominator among human cancers. How was it discovered? What are the persistent questions about its function? Aa Aa Aa It seems nearly impossible for a normal cell to become a ...

The findings were recently published in Communications Chemistry. p53 is central to the body's defense against cancer, tasked ...

By Pooja Toshniwal Paharia Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and ...

p53 and RB are at the heart of the two main tumour-suppressor pathways that control cellular responses to potentially oncogenic stimuli. Each pathway consists of several upstream regulators and ...

Astex data presentations at 36th EORTC-NCI-AACR Symposium, 23rd-25th October 2024, Barcelona ...

"Then, when we added loss of the p53 oncogene, the mice developed bona fide invasive prostate cancer. “It will be an addition ...

Presentation Details: Title: CLSP-1025, a novel bispecific T cell engager targeting a p53 R175H mutant peptide presented by HLA-A*02:01 Presentation Type: Poster Abstract Number: 1061 Date and ...

It focuses on its lead product candidate, ALRN-6924, which is a cell-permeating peptide that disrupts the interaction of p53 suppressors MDM2 and MDMX with tumor suppressor p53 to reactivate tumor ...

The aim of the present work was to establish an association between wood smoke exposure and lung cancer pathogenesis, and to analyze the effects of wood smoke on p53 and murine double minute 2 ...

From rental payments for safe houses that dwarf what is paid for most five-star hotel overnight stays to spending for “youth ...

Administration and opposition lawmakers in the House of Representatives stood pat on their decision to keep the slashed ...

Tobacco smoke is still considered the main cause of lung cancer. After decades of antismoking campaigns, a constant increase in lung cancer cases around the world could be an indicator that ...