Scripps researchers have developed a new paradigm for simply introducing non-canonical amino acids to proteins. Their ...

In chemistry, an amino acid is a molecule that contains both amine and carboxyl functional groups. In biochemistry, this term refers to alpha-amino acids with the general formula H2NCHRCOOH, where ...

The first amino acid, discovered in 1806, had a disarmingly ordinary source: asparagus juice. Hence the name asparagine. The next amino acids to be discovered had sources that were, if anything ...

There are 20 standard amino acids that are commonly found in proteins. These amino acids can be classified based on various criteria, such as their essentiality, ... Non-Polar Amino Acids: These amino ...

In this study, the researchers focused on para-nitro-L-phenylalanine (pN-Phe), a non-standard amino acid that is neither one of the twenty standard amino acids nor been observed in nature. pN-Phe has ...

Non-standard amino acids are the basis of protein drugs from GRO Biosciences, a Cambridge-based startup based on research from Harvard. GRObio’s lead program is proceeding toward clinical ...

Press Release GRO Biosciences Inc. ("GRObio"), an emerging biotechnology company leveraging synthetic biology to expand the amino acid alphabet and deliver on the promise of protein therapeutics ...

Some of these may have relied on non-standard amino acids, possibly formed in environments like alkaline hydrothermal vents, ...

Amino acids are the individual building blocks of proteins and are essential for biological systems to work properly. There are 20 standard amino acids that make up proteins in all living systems ...

Even with this limitation it's possible to incorporate non-standard amino acids into the genetic code 2. Though not ideal, this approach still works surprisingly well.

The Company’s genomically recoded organism (GRO) platform enables precise placement of non-standard amino acids (NSAAs) within a protein to realize previously unattainable therapeutic capabilities.