Chronic pain affects millions of people in the US. Targeting an oft-overlooked brain receptor could one day offer relief.

Scientists have discovered novel drug candidates which could ultimately lead to new effective treatments for conditions ...

Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a ...

Neuropathic pain doesn’t just affect the body – it also alters the brain. Chronic pain of this nature often leads to depression, anxiety, social isolation and a deep sense of helplessness.

A painkiller developed by Germany's Algiax Pharma has shown efficacy in the treatment of chronic neuropathic pain, another positive development in the search for alternatives to opioids. The phase ...

Neuropathic pain is caused by disorders of, or damage to, the nervous system. The affected nerves can induce the sensation of pain in the brain. Neuropathic pain is often associated with the ...

Vertex Pharma's non-opioid painkiller suzetrigine was unable to perform better than placebo in a phase 2 trial in lumbosacral radiculopathy (LSR), a form of neuropathic back pain, ahead of an FDA ...

If nerve signals to the muscles in the blood vessels are shut down, the vessels stop working properly. A stroke or blood clot that prevents blood from circulating can also bring on neurogenic shock.

The efficacy of pregabalin for the management of neuropathic pain associated with diabetic peripheral neuropathy has been established in several controlled clinical trials. [17, 18, 19] These ...