The discovery of Mycobacterium lepromatosis suggests leprosy was present in the Americas long before Europeans, altering the historical understanding of the disease.

Galectins form a protein family with a conserved carbohydrate-binding domain that specifically interacts with β-galactoside-containing glycoconjugates, which are found abundantly on mammalian cell ...

In a lab in the heart of Boston, professor Bree Aldridge leads a team of researchers trying to understand a threat that is both microscopic in size and global in consequence. The subject of Aldridge’s ...

Granuloma structure and distribution of the antibiotic BTZ-043 in differently stained tissue sections of two tuberculosis granulomas. The stains show (in z-shaped order from top left to bottom right): ...

Granuloma structure and distribution of the antibiotic BTZ-043 in differently stained tissue sections of two tuberculosis granulomas. The stains show (in z-shaped order from top left to bottom ...

Infection with the related bacillus, Mycobacterium leprae, is one of the most common causes of neuropathy in the world. 13 This may present as lepromatous leprosy (with infiltration of the nerve by ...

Swimming pool granuloma is a rare infection of the skin caused by Mycobacterium marinum. The primary skin lesion is defined as a blue/red papule or nodule with verrucous surface and secondary ...

Profile of Lalita RamakrishnanThe experience solidified Ramakrishnan’s interest in tuberculosis (TB), a disease she was familiar with. She had seen her mother go through three bouts of TB, and as a ...

Ramakrishnan went on to develop a model for studying TB using the bacteria Mycobacterium marinum in zebrafish. The model enabled groundbreaking discoveries about TB pathogenesis, drug tolerance, and ...

This paper describes a method for incorporating a diffusion field modeling oxygen usage and dispersion in a multi-scale model of Mycobacterium tuberculosis (Mtb) infection mediated granuloma formation ...