When lipid biologist Usha Acharya at the National Cancer Institute (NCI) tinkered with lipid breakdown pathways in Drosophila ...

Ferroptosis offers new strategies to combat treatment resistance in digestive tract cancers, enhancing the efficacy of ...

The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant ...

Chronic liver disease (CLD) is a growing global health challenge, accounting for millions of deaths each year. Its major contributors include ...

Importantly, the gene is linked to hepatocyte lipid accumulation and, by extension, to conditions like hepatic steatosis. Its loss-of-function mutation, rs72613567, results in a truncated, inactive ...

In the manuscript "FABP4-mediated lipid accumulation and lipolysis in tumor-associated macrophages promote breast cancer metastasis", Yorek, et al. provide a novel mechanism explaining how unsaturated ...

Recent studies have shown that lipid accumulation in TAMs can promote tumor growth and metastasis in various models. However, the specific molecular mechanisms that drive lipid accumulation and tumor ...

Lipid droplets (LDs) serve as crucial hubs for lipid trafficking and metabolic regulation through their numerous interactions with various organelles. While the interplay between LDs and the Golgi ...

High cholesterol can increase a person's risk of heart disease, as it causes a fatty-lipid substance known as cholesterol to ...

It’s a theory that outlines key elements in price trend development that are marked by periods of accumulation and distribution. Four distinct phases comprise the cycle: accumulation ...