The 49ers know firsthand how difficult it is to defeat the Chiefs, even if the numbers say Mahomes and Kansas City's offense ...

The San Francisco 49ers have demons to slay in Week 7 when they face the Kansas City Chiefs in a rematch of Super Bowl 58.

After a sluggish first quarter, the first score was once again a 55-yard field goal, and Mecole Hardman continues to be a ...

The 49ers were without three of their top playmakers for much of the matchup, with running back Christian McCaffrey (Achilles ...

Sunday's Super Bowl rematch between the Kansas City Chiefs and San Francisco 49ers didn't produce the fireworks many expected, as quarterbacks Patrick ...

Newsweek's guide to how to bet Chiefs vs. 49ers breaks down Sunday afternoon's must-see battle between the reigning champs ...

The Kansas City Chiefs traveled to face the San Francisco 49ers in Week 7, and there was plenty to take away from the Sunday ...

Saquon Barkley had 176 rushing yards and a touchdown in his return to New York to face the Giants, while Deshaun Watson ...

Kansas City's defense ruled the day as Brock Purdy threw three interceptions and the 49ers lost Brandon Aiyuk due to injury.

FOX Sports' NFL experts break down Sunday's Super Bowl rematch between the Chiefs and 49ers, including key players, matchups and analysis.

By the time the Kansas City Chiefs took the field Sunday at San Francisco, they already were the lone remaining unbeaten team ...

The San Francisco 49ers will host the Kansas City Chiefs at Levi's Stadium in Santa Clara, California, on Sunday, October 20, ...