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The synapse Davis refers to is the immunological synapse, where T cells receive their marching orders; understanding it is vital to appreciating how an immune response is set in motion. "We like to ...
Immunological synapse (IS) formation is a key part of developing and sustaining immune responses against cancer and is necessary for T cells and NK cells to eliminate tumor cells. This webinar will ...
The immunological synapse is the crossroads of the adaptive immune system, through which helper T cells instruct B cells to induce antibody production or killer T cells latch onto infected and ...
The immunological synapse is a thing of beauty to behold under a microscope but the kiss of death for a cancer cell. "Synapse" is the word used to describe prolonged contact between a T cell and ...
The study, published in the November 18, 2005, issue of Science, reveals how T cells analyze and react to the signals of infection at the immunological synapse.
This CD2-CD58 interaction is crucial for immune cell activation and adhesion, playing a significant role in forming the immunological synapse, which is vital for effective immune responses.
Switching immune cells on is a critical step in combating infection. In the case of T cells, which are key players in immunity, this happens when dormant T cells circulating in the blood encounter ...
Immunological synapse formation is essential for T cell activation. A recent paper in Science reports that immunological and neurological synapses utilize a common molecule, agrin.
Actin reorganization at the immunological synapse is required for the amplification and generation of a functional immune response. Using small interfering RNA, we show here that dynamin 2 (Dyn2 ...
In mice that express LAG3 (left image), accumulation of LAG3 at the immunological synapse in T cells lowers the pH, making conditions more acidic (green and blue) compared with less acidic (red ...