Colon cancer is the second leading cause of cancer-related deaths globally. This cancer often develops silently, with symptoms emerging only in later stages. Early detection can significantly ...

The Phase 1 program, which included single ascending dose (SAD), multiple ascending dose (MAD), and cross-over food effect (FE) studies in adult healthy volunteers, as well as a small cohort of UC ...

PK analysis confirmed the delayed-release, terminal ileum-targeted and colon-targeted profile of PALI-2108.Plasma and tissue PK demonstrated that therapeutically relevant concentrations (above ...

Palisade Bio Reports Positive Phase 1a Results for PALI-2108, a First-in-Class Terminal Ileum and Colon-Targeted PDE4 B/D Inhibitor for Fibrostenotic Crohn’s Disease and Ulcerative Colitis ...

Carlsbad, CA, May 27, 2025 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade”, “Palisade Bio”, or the “Company”), a clinical-stage biopharmaceutical company focused on developing and ...

If the surgeon can’t join the ends of the healthy intestine, they do a colostomy or ileostomy. The surgeon makes an opening (stoma) in your belly. Then they attach the top end of your colon or ileum ...

The colon cancer mortality rate in people under 55 has been rising about 1% annually since the mid-2000s. Getty Images Citing a 2023 study, gastroenterologist Joseph Salhab recently shared on ...

In the new study, published Apr. 3 in Gastroenterology, the investigators showed that in a preclinical model of short bowel syndrome, deleting the colon gene SATB2 prompts cells of the upper colon ...

In the new study, published Apr. 3 in Gastroenterology, the investigators showed that in a preclinical model of short bowel syndrome, deleting the colon gene SATB2 prompts cells of the upper colon ...