Javier Martínez-Picado is one of the leading researchers in the fight against AIDS and coordinates the international consortium IciStem from Barcelona. Behind some of the most important recent ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors ... occurs in the later stages of infection as ...

Aphios announced today that it was awarded an NIH SBIR grant from the National Institute on Aging (NIA) to develop anti-CCR5 nanoparticles to treat Alzheimer's disease. Alzheimer's disease and ...

We call them farms but the great bulk of food producing businesses in the west are better described as agricultural ...

The basis of this approach is Adaptive’s immunosequencing technology, which provides high-throughput sequencing of T-cell receptors ... with HIV serving as a particularly useful substrate. Because HIV ...

NNRTIs bind to a hydrophobic pocket near the catalytic site of HIV-1 RT and inactivate enzymatic activity. NNRTI-resistance mutations & their mechanism of drug resistance The most prevalent NNRTI ...

The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...

Dec. 11, 2024 — Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to ...

Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one ...

The potential mutation would allow the avian influenza virus sweeping through dairy herds to attach to a receptor protein on ...

(Humans also have avian-type receptors, but they’re not located in parts of the body that promote H5N1 transmission between people.) Previous studies have found that mutations at certain ...