Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of ...

Traumatic brain injury, stroke, and degenerative diseases elicit complex pathogenic cascades involving glial cells such as astrocytes, microglia, and ...

Understanding these shared metabolic pathways opens new avenues for improving both crop resilience and human nutrition. The study focuses on lysine catabolism. Catabolism, the breakdown of ...

Metabolic pathway enrichment was accomplished via MetaboAnalyst V.5.0.28 GraphPad Prism V.9.0 (GraphPad Software) was used for statistical treatment. Experimental data was shown as mean±SEM.

However, glutamate kept stable in both groups (Figure 1E and F ... Based on KEGG datasets, activities of cysteine and glutathione metabolism pathways were found dysregulated in JIMT1 cells (Figure 2D) ...

However, several Trp metabolism end-products are essential to intestinal homeostasis. Here, we investigated the role of metabolites from the kynurenine pathway. Design Targeted quantitative ...

An additional cyclic pathway for the metabolism of hexose phosphate has recently come to light. This pathway (Fig. 10) appears to function in the synthesis of ascorbic acid, with uronic acids as ...

Venous blood was collected at 7:30–8:00 am before breakfast. Based on the results of untargeted metabolomics, a glutamate metabolism pathway was noticed. Glutamate is a very important excitatory ...

Here, we describe a computational method that predicts the functions of orphan enzymes by organizing them into a linear metabolic pathway. Given candidate enzyme and metabolite pathway members, this ...