Few questions have captivated humankind more than the origin of life on Earth. How did the first living cells come to exist? How did these early protocells develop the structural membranes necessary ...
Researchers at UC San Diego have examined the critical role of goblet cells in gut immunity and health. GCs create a mucus ...
This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...
In this Thought Leader article., Ian Johnston from Cytiva discusses challenges related to process development, scaling technology, regulatory approvals, and GMP guidelines.
Ding, B. , Wu, Y. , Zhang, Y. and Li, Y. (2024) CXCL10 Induces Lytic Reactivation of EBV through EXTL 1. Advances in ...
Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...
Tethered bilayer lipid membrane (tBLM) is another avenue that can be used prepare lipid bilayers to mimic the cell surface. In a tBLM system, a synthetic bilayer is formed on a tethered surface. This ...
These membranes, composed of flexible lipid bilayers, can reshape and remodel themselves during processes like cell movement, division, and molecular trafficking. Until now, it was commonly assumed ...
LNPs carrying mRNA need to arrive at the cells, where they will be taken in through a process known as endocytosis. There, the cell breaks the LNP carrier, which allows the mRNA cargo to be released.
Ubiquitously targeting cells within a tumor is not always feasible because some drugs cannot diffuse efficiently, and the random nature of the approach makes it difficult to control the process.