The ΨA base pair at the first position is accompanied by the formation of purine–purine base pairs at the second and third positions of the codon, which show an unusual Watson–Crick/Hoogsteen ...

They showed that a short mRNA sequence—even a single codon (three bases)—could still bind to a ribosome, even if this short sequence was incapable of directing protein synthesis.

In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

A codon is a sequence of three bases which join up to create a unit of DNA information. One codon directs one building block known as an “amino-acid” in a protein.

START codons The codon AUG is called the START codon as it the first codon in the transcribed mRNA that undergoes translation. AUG is the most common START codon and it codes for the amino acid ...

Every basic biology lesson teaches that proteins are made up of combinations of 20 distinct amino acids, which are ordered in various patterns similar to words.

If the anticodon does not match the codon, base pairing cannot happen and the tRNA is rejected. Then, the ribosome moves one codon forward making space for a new tRNA-amino acid complex to enter.

One codon, two amino acids – it’s a unique set-up and further proof that the genetic code, universal though it almost is, is open to expansion and evolutionary change.