Considering the prominent role of inflammatory elements in the lung microenvironment and emerging evidence positing the lung as a niche of hematopoietic progenitor cells, clonal hematopoiesis (CH) may ...

This work is published in Nature in the article, “Clonal tracing with somatic epimutations reveals dynamics of blood ageing.” In youth, humans have between 50,000 to 200,000 active blood stem ...

Clonal hematopoiesis (CH) is an age-related process characterized by mutations in hematopoietic stem/progenitor cells (HSPCs), most commonly in the DNMT3A gene. In CH, mutant HSPCs gain a ...

Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, China. (Y.T., X.Z., C.Z., X.C., G.Z., T.M., S.Y.) Center of Coronary ...