Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital and Baylor College ...

In late adolescence and adulthood, BPAN can cause symptoms similar to dementia. In the study, developing mice embryos were injected with CAS9 and RNA corresponding to specific BPAN patients’ genetic ...

Against the backdrop of a Cas9 patent battle that refuses to die, Editas Medicine is cashing in a chunk of the licensing rights from Vertex Pharmaceuticals to the tune of $57 million. Last last ...

Cas9, a technology that has moved from lab to clinic at lightning speed. Scientists have already used gene editing to improve ...

“After treating mice with T-cell-targeted vectors ... Promoters are DNA sequences that help to regulate Cas9 expression in CRISPR-Cas9 editing. NLSs are amino acid sequences that support Cas9 in ...

Here are some of the most groundbreaking developments in science this week, ranging from a novel approach to rejuvenating ...

Cas9, the first Cas protein repurposed for cutting DNA, introduces double-strand breaks that recruit DNA repair machinery. Despite its successes, the CRISPR-Cas9 system has several limitations, ...

Brunet and colleagues described their findings in Nature, in a paper titled “CRISPR–Cas9 screens reveal regulators ... which is many millimeters away in a mouse brain.