BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early ...

A new study led by Harvard Medical School researchers shed new light on how even a single defective copy of the ...

Cancer is primarily a genetic disease that is clonal in nature. It usually starts when a single cell acquires a series of mutations, usually one after another, that collectively change a once ...

In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the ...

When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing cancer. There are many types of EGFR mutations. The EGFR protein lives in the cell membrane with ...

Those mutations have long been known to be at the root of cancer, but whether they were important for ageing has been debated for decades. Researchers at Sanger say they have produced "the first ...

Scientists discovered the cancer-causing cell with a genetic mutation that causes a common variant of breast cancer first emerges in patients around the age of puberty. A team of researchers ...

The scientists, including researchers from National Cancer Center Japan (NCC), said it remains unclear what causes the mutation pattern, so an unknown carcinogenic factor peculiar to Japan likely ...

Missense variants not found in cancer often retain some residual activity, and outlier mutations linked to cancer sometimes involve splice alterations. The strong correlation between loss of ...