Effector CD4⁺ T cells restore antiviral CD8⁺ T cell function in the liver by licensing Kupffer cells via CD40–CD40L interactions. This triggers IL-27 production and reprograms the hepatic ...

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Explore the latest advances in immunosuppression research that may bring transplant patients closer to the goal of having "one organ for life". Learn about new developments in organ transplant and ...

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The DRiP hypothesis proposes that most peptides that bind to MHC class I molecules are derived from newly synthesized defective proteins. Here, the authors revise this hypothesis and propose that ...