Patients with antiphospholipid antibodies (aPL) are at increased risk for arterial or venous thrombosis. There is, however, significant heterogeneity among patients according to clinical and ...

Atrial fibrillation (AF) is a major cause of ischemic stroke, especially in the elderly. There are currently enough data to support the notion that anticoagulation with warfarin or dabigatran is ...

1 Department of Medicine, University of Wisconsin School of Medicine and Public Health, 3116 MFCB, 1685 Highland Avenue, Madison, WI 53705, USA. 2 Division of Electrophysiology and Cardiovascular ...

Methods and analysis We will search PubMed, Cochrane Central Register of Controlled Trials and Embase using a strategy that combines the terms aspirin, bleeding/ischaemic and neurosurgery. Two ...

Aspirin prodrugs formed by derivatization at the benzoic acid group are very difficult to obtain because the promoiety accelerates the rate of hydrolysis by plasma esterases at the neighboring acetyl ...

A large real-world Italian cohort study found that daily low-dose aspirin use significantly lowered the risk of developing type 2 diabetes, especially during the COVID-19 pandemic. The protective ...

Compared with aspirin, clopidogrel reduces risk of mortality, myocardial infarction (MI), and stroke after percutaneous coronary intervention (PCI) and completion of a standard duration of dual ...

Aspirin in Primary Prevention: Need for Delineating High CV-Risk, Low-Bleeding-Risk Profiles: Aspirin in primary prevention requires a nuanced, risk-stratified approach to balance CV benefits with ...

CHICAGO — Daily adjuvant aspirin did not reduce disease recurrence for patients with colorectal cancer liver metastases and may increase risk for death, according to findings presented at ASCO ...

Resistance and nonresponse to aspirin dramatically decreases its therapeutic efficacy. To overcome this issue, a small-molecule thrombus-targeting drug delivery system, aspirin-Arg-Gly-Asp-Val (A-RGDV ...

High-dose aspirin (HDA) is used with intravenous immunoglobulin (IVIg) in Kawasaki disease (KD). Practice regarding HDA varies, and it is unclear whether HDA duration affects the long-term course ...