Mesothelioma Clinical Trials and Studies: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies
DelveInsight’s, “Mesothelioma Pipeline Insight 2025” report provides comprehensive insights about 45+ companies and 50+ ...
Frontiers1mon
Deciphering and engineering the polyunsaturated fatty acid synthase pathway from eukaryotic microorganisms
In eukaryotes, PUFAs can be de novo synthesized through two independent biosynthetic pathways: the desaturase/elongase pathway and the PUFA synthase pathway. Among them, PUFAs synthesized through the ...
Nature10mon
Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation
Crystal structures of human endothelial nitric oxide synthase (eNOS) and human inducible NOS (iNOS) catalytic domains were solved in complex with the arginine substrate and an inhibitor S ...
Frontiers2y
Predictive markers for efficiency of the amino-acid deprivation therapies in cancer
Arginine is synthesized from citrulline in two steps: (1) Argininosuccinate synthase converts L-citrulline and aspartic acid to argininosuccinate; (2) argininosuccinate lyase converts ...