Controlling cardiovascular risk factors and maintaining long-term disease remission mitigated the increased risk for ...

RAY-121 is under clinical development by Chugai Pharmaceutical and currently in Phase I for Antiphospholipid Syndrome.

The primary safety endpoints are toxicities — including cytokine release syndrome, ICANS, organ toxicity and hematotoxicity, at grade 2 or higher for all — while efficacy endpoints are DORIS ...

β 2-glycoprotein I (β 2-GPI) is a natural inhibitor of the platelet-VWF interaction. The antiphospholipid syndrome (APS) is associated with thrombosis, with an important pathophysiological role of ...

Catastrophic antiphospholipid syndrome (CAPS) is a rare and life threatening complication of antiphospholipid syndrome. Up to half of people with CAPS die, so timely treatment is essential.

Angelman syndrome is a rare disease that disrupts the normal development and function of cells, particularly in the nervous system, leading to severe developmental delays and learning disabilities.

But for a small number of children, the infection triggers strange behavior changes known as PANDAS syndrome. PANDAS stands for Pediatric Autoimmune Neuropsychiatric Disorders Associated with ...

Background: Antiphospholipid syndrome (APS) is an autoimmune disease characterized by recurrent vascular thrombotic events. Catastrophic APS (CAPS), which can result in multiple organ failure and even ...

Aim: To determine the association between single-time-point measurement of aPL and atherosclerotic cardiovascular risk in a diverse population without established cardiovascular disease or ...

, Yale University School of Medicine; , St. Mary's Hospital; , Yale University School of Medicine LAC testing is also problematic for the clinician. Not all hospitals and clinical laboratories use ...

A study reveals chronic sinusitis may increase rheumatic disease risk by 40%, especially 5-10 years before symptoms. Sinusitis inflames nasal passages, obstructs mucus flow, and hampers breathing. The ...

Antiphospholipid syndrome (aPS) is a thrombotic disorder characterized by persistent venous and arterial thrombosis, potentially resulting in any symptoms related to those disorders, including balance ...