Progress concerning second-line choleretic drugs is evident, but long-term beneficial outcomes of new agents should be estimated in phase IV trials. The updated concepts of treatment endpoints and new ...

This suggests that adiponectin may serve as a potential biomarker for identifying advanced liver cirrhosis. Levels of adiponectin are significantly elevated in patients with primary biliary ...

Expanding the indication of EFG-α to other autoimmune diseases, including SLE, and its use in pediatric patients should be considered. Efgartigimod alfa (EFG-α) may be an effective treatment for not ...

Transcriptomic and immunohistochemical analyses revealed the therapeutic potential of inflammasome blockade in chronic histiocytic intervillositis. Targeting the inflammasome pathway with anakinra and ...

At a recent support group meeting for alpha-1 antitrypsin deficiency (AATD) patients, someone asked me a question I wasn’t expecting. He asked if I thought coffee was good for AATD patients. I did a ...

Peripheral blood smear showed erythrocyte agglutination, polychromasia, and anisocytosis. The direct antiglobulin test was positive for C3d and IgM, confirming CAD. Elevated cold agglutinin titers ...

As he returns to exercise, a columnist with multiple sclerosis (MS) considers the benefits of exercise and recommends targeted programs. I’ve returned to exercising for the first time in about 5 ...

Expert consensus suggests that the treatment of individuals with concurrent PNH and AA should largely depend on the predominant disorder. The treatment of patients with concurrent paroxysmal nocturnal ...

Further studies are needed on the efficacy of novel alternative complement inhibitors and anticoagulants in preventing thrombolytic events. A new literature review has been published updating current ...

The models could decrease unnecessary testing by 28% but missing approximately 9% of patients with positive NGS findings. A simple testing algorithm based on single-cutoff values for red blood cells ...

Adequate antenatal care is key to identifying and treating fetal and neonatal alloimmune thrombocytopenia (FNAIT) in a timely manner. Neonatal thrombocytopenia, of which fetal and neonatal alloimmune ...

There were several efficacy parameters in this study that showed numerical results greater than those seen in the placebo group. Intravenous immunoglobulin (IVIG) maintenance therapy appears to cause ...