Background Obstructive sleep apnoea syndrome (OSAS) is characterised by repeated apnoea’s due to partial or total collapse of the upper airway during sleep, resulting in fragmentation of sleep and ...

Background Reduced forced expiratory volume (FEV 1) and forced vital capacity (FVC) are risk factors for myocardial infarction (MI) and stroke. However, the relationship with incidence of heart ...

Background A challenging problem arising from cystic fibrosis (CF) newborn screening is the significant number of infants with hypertrypsinaemia (HIRT) with sweat chloride levels in the intermediate ...

Introduction UK national guidance for screening for tuberculosis (TB) has changed over the years. This study retrospectively evaluated the shifts across three cohorts of latent TB cases managed over a ...

Introduction and Objectives Metered Dose Inhalers (MDIs) account for 3% of NHS carbon emissions. In April 2022, NHS England introduced two indicators focussed on reducing avoidable carbon emissions ...

1 Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong 2 Department of Psychiatry, Shatin Hospital, The Chinese University of Hong Kong, Shatin, ...

Asthma exacerbations are common. They account for a significant morbidity and contribute a disproportionate amount to the cost of asthma management. The optimal strategies for the prevention of asthma ...

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Introduction Air pollution is associated with increased asthma-related admission rates (Lancet, 2014;383(9928):1581–92). The impact of pollution on outcomes of monoclonal antibody (MAb) therapy in ...

Background High flow oxygen (HFO) is an acute non-invasive intervention for the treatment of hypoxaemia. It is increasingly used in patients who are near End of life (EOL). Aims and Objectives To ...

Introduction The pathogenesis of sarcoidosis involves tissue remodelling mediated by the accumulation of abnormal extracellular matrix, which is partly the result of an imbalance in collagen synthesis ...