Instead of being used for something, the codon was freed up to be redefined. The researchers did similar experiments with the codons for the amino acid serine.

Article #20-14567: "Evolution of the genetic code; Evidence from serine codon use disparity in Escherichia coli," by Masayori Inouye, Risa Takino, Yojiro Ishida and Keiko Inouye.

Code-breaking codon. Published 3 March 2010. ... Therefore the code is not universal, although it can be called widespread as, for example, the codon TCT codes for serine in any organism.

This is odd enough in itself. But the team was even more surprised to find one species, Ascoidea asiatica, randomly translated this codon as serine or leucine.Every time this codon is translated ...

He and his team systematically replaced every occurrence of the serine codon TCG with AGC, every TCA (also serine) with AGT, and every TAG (stop) with TAA, for a total of 18,214 replacements.

The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...

In humans and most other living things, the codon CTG translates to the amino acid leucine. But in this yeast family, some members use the sequence to create serine, while others make alanine out ...

Serine homopolymers generally have higher codon diversity than other amino-acid repeats in D. discoideum (Eichinger et al., 2005), but the poly-S 306 ranks in the top 5 of 81 even among serine ...

In the CDR3 of VL there are two hot spots of the A/G-G-C/T-A/T type and one AGT serine codon. We began our experiments by concentrating on the tetranucleotide hot spots in VL CDR3.

For instance, the codon TCG tells its matching tRNA to attach the amino acid serine. In this case, the Cambridge team had deleted TCG along with sister codon TCA, which also calls for serine.

But the team was even more surprised to find one species, Ascoidea asiatica, randomly translated this codon as serine or leucine. Every time this codon is translated the cell tosses a chemical ...