NFL odds, Week 16 lines, ATS predictions, game picks, tips, times: Model simulates each game 10,000 times
While many bettors would prefer to make Week 16 NFL predictions and Week 16 NFL game picks with narrow lines, others would prefer heavy NFL favorites or NFL underdogs go bet on. Fortunately, both of those groups are in luck thanks to the wide spectrum of Week 16 NFL spreads.