By targeting surface markers on cancer cells, engineered synthetic receptors expressed on immune cells can be directed to ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

While not specific to determining the precise localization of NPs, rather confocal and transmission electron microscopy are pertinent, flow cytometry ... as to the intracellular and extracellular ...

Animal models enable more convenient access to tissue samples and have allowed to investigate the spleen using techniques such as multiparameter flow cytometry in a great ... non-specific cellular ...

Introduction: As the golden approach of single-cell analysis, fluorescent flow cytometry can estimate single-cell ... were used for fabricating constrictional microchannels. Membrane and intracellular ...

Methods Here, we characterised a kindred of two monozygotic twin girls with juvenile idiopathic arthritis at the genetic and immunological level, using whole exome sequencing, single cell sequencing ...

Gating was based on the MDL-AID KO control cell line stimulated with the citrullinated antigen and on Isotype control staining’s using mouse IgG1 ... Stained cells were analysed on a BD LSR-II flow ...

Intracellular distribution of viral mRNAs indicated that ... Supplementary figure 5. We thank Imaging and Flow Cytometry Core, The Centre for PanorOmic Sciences (CPOS), LKS Faculty of Medicine of The ...

Haematoxylin and eosin (H&E) and picrosirius red staining with quantification by morphometric ... The authors would like to thank Patrice McDermott (Human Vaccine Institute Flow Cytometry Core ...