Ask yourself how the genetic test results may affect your life. If the results come back positive, will you take steps to ...

The fragile structure of p53 gene reveals why this crucial cancer defense is so easily compromised, shedding light on the genetic Achilles' heel of many tumors. In a recent perspective published in ...

A study released by the National Cancer Center Japan has revealed higher rates of mutations in a tumor-suppressing gene, TP53, in Japanese cancer patients compared to those in the United States.

Polymorphisms in upstream activators, repressors or downstream effectors of p53 might individually modulate cancer risk or interact with polymorphisms or mutations in TP53. Because the effects of ...

Dr. Cornelia Peterson is dedicated to finding treatments for cancer by researching tumors that develop in Meibomian glands, ...

The test, done at Poole Hospital, identified two key genes driving her cancer, ALK fusion and TP53, and doctors prescribed brigatinib, a drug that targets the ALK gene. “Having the ctDNA test results ...

Prince Harry 's ex-girlfriend Cressida Bonas is remembering her late sister Pandora with love.

A new phase 1 trial demonstrates the safety and effectiveness of personalized neoantigen DNA vaccines, showing promising ...

A 31-year-old woman with stage IV breast cancer learns a test ordered more than a year before her diagnosis detected a TP53 ...

AMSBIO’s CancerSeq™ FFPE tissues provide pre-screened tumour samples validated for single nucleotide polymorphisms (SNPs), ...

Saturation mutagenesis revealed that over half of TP53 missense variants lead to a loss of function, similar to indel variants. Missense variants not found in cancer often retain some residual ...