in the fold of the serine-threonine phosphatase-1 subfamily 19. The crystal structure of one member of this family was solved in 1995, but the location of the putative redox regulatory site was ...
A team from the University of Washington led by Nobel laureate David Baker is using artificial intelligence to design effective enzymes from scratch — an accomplishment the researchers call "one of ...
The company discovered Serine Protease Inhibitors ... At the same time, he unveiled a new organizational structure to best ...
Recombinase efficiency increases allow Qi Biodesign to insert 20-30 kb (5 or 6 genes) at one time at one location across a variety of different crop genetics. In addition, a large team at Qi Biodesign ...
Crafting enzymes is more difficult than designing other proteins because it requires not just predicting the structure of a single ... to identify designs for serine hydrolase enzymes to test ...
Designing enzymes, unfortunately, is very hard. It’s like working with an atom-sized Lego set, but the instructions are lost ...
Animation showing the transition state of a serine protease—an example of ... view among biophysicists that enzymes are not a single structure. Instead, they focus on what they term "ensembles ...
Silk’s amino acid sequences—like glycine-alanine and glycine-serine—give fibers strength, while elastin’s molecular structure adds stretchiness. Combine these molecules like Lego blocks, ...
Assessment of transfer entropy is useful for network analysis of cell signaling network providing information on the network topology and action points of genetic mutations and drug effect, thus will ...
To test their cutting-edge approach, the UW researchers focused on a well-studied enzyme called a serine hydrolase. The enzyme is able to cleave a chemical bond that’s key to the structure of ...
The specific structure of a protein is key to its function ... We used this AI model specifically to generate enzymes called serine hydrolases, a group of proteins that have potential applications ...
Enzymes significantly speed up the chemical reactions that keep you alive. Researchers are using AI to create new ones to tackle modern challenges.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback