The pathway leading to the telltale sign of ALS, protein aggregation in the cytoplasm of motor neurons, has been revealed.

The mechanisms underlying skin renewal are still poorly understood. Interleukin-38 (IL-38), a protein involved in regulating ...

The mechanisms underlying skin renewal are still poorly understood. Interleukin-38 (IL-38), a protein involved in regulating inflammatory responses, could be a game changer. A team has observed it for ...

causing protein aggregates. These aggregates accumulate within a cell's mitochondria, an organelle that generates the energy needed to power a cell's biochemical reactions. Without functioning ...

An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this ...

Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas ...

ABOVE: Hematopoietic stem cells have mechanisms in place to generate intrinsically disordered proteins, which could underlie ...

The misfolded proteins interact and aggregate. We’ve developed a polymer that can fight those interactions.” The new study builds on previous work from Qi’s laboratory at Case Western Reserve. In 2016 ...

Highlights: Positive preclinical results in human in vitro iPSC Motor Neuron models of Amyotrophic Lateral Sclerosis (ALS) ...

Aggregates and small fractions of ‘oversized’ particles can significantly impact the quality and safety of nanosuspensions.

An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this mechanism is disrupted, the blueprints used by the cell to produce proteins are ...